CASE REPORT Hypoparathyroidism mimicking ankylosing spondylitis and myopathy: a case report

نویسندگان

  • Thayana Ribeiro Kajitani
  • Renata Viana da Silva
  • Eloisa Bonfá
  • Rosa M. R. Pereira
چکیده

Idiopathic hypoparathyroidism (HP) is an induced or inherited condition characterized by insufficient secretion of parathyroid hormone. The clinical manifestations of this condition are varied, and pain and stiffness affecting the back and hips resembling ankylosing spondylitis is an under-recognized symptom in these patients. Here, we report a case of delayed diagnosis of hypoparathyroidism referred to a rheumatologist due to progressive inflammatory back pain and myalgia. Idiopathic hypoparathyroidism is an induced or inherited condition of unknown etiology and is characterized by insufficient secretion of parathyroid hormone due to atrophy or absence of parathyroid glands, which leads to hypocalcaemia and hyperphosphatemia. Hypoparathyroidism has multiple clinical manifestations, which primarily involve tissues of ectodermic origin. Pain and stiffness affecting the back and hips, limited movement and posture resembling that seen in patients with ankylosing spondylitis is an under-recognized feature in patients with this condition. Muscular complaints by these patients are common because the concentration of calcium ions is important for the maintenance and control of several biochemical processes during muscle contraction. Hypocalcaemia causes hyperexcitability of nerves and muscles, and a sporadic increase in muscular enzymes. Here, we report a case of delayed diagnosis of hypoparathyroidism referred to a rheumatologist due to progressive inflammatory back pain and myalgia with concomitant elevation of inflammatory markers and muscle enzymes. The patient was initially erroneously diagnosed with ankylosing spondylitis (AS) and idiopathic myopathy. This case reinforces the relevance of investigating the underlying mineral metabolism disturbances in patients with inflammatory diseases.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Hypoparathyroidism mimicking ankylosing spondylitis and myopathy: a case report

Idiopathic hypoparathyroidism (HP) is an induced or inherited condition characterized by insufficient secretion of parathyroid hormone. The clinical manifestations of this condition are varied, and pain and stiffness affecting the back and hips resembling ankylosing spondylitis is an under-recognized symptom in these patients. Here, we report a case of delayed diagnosis of hypoparathyroidism re...

متن کامل

Idiopathic Hypoparathyroidism Mimicking Ankylosing Spondylitis: A Case Report.

Idiopathic hypoparathyroidism, inadequate secretion of parathyroid hormone of unknown etiology, may mimic ankylosing spondylitis both clinically and radiologically. Spinal complaints may be the first sign of any endocrinological disorder.

متن کامل

Hypoparathyroidism as the First Mani-Festation of Kearns-Sayre Syndrome: A Case Report

Kearns-Sayre syndrome is a mitochondrial myopathy, which was first described by Tomas Kearn in 1958. Diagnostic symptoms of this condition include retinitis pigmentosa, chronic progressive external ophthalmoplegia, and one or more of the following factors: cardiac conduction system diseases, cerebellar ataxia, and cerebrospinal fluid (CSF) with protein content above 100 mg/dL. The nature of thi...

متن کامل

Disseminated Tuberculosis Mimicking Ankylosing Spondylitis

Ankylosing spondylitis is a chronic inflammatory disorder affecting mainly the axial skeleton. Here we report a case of a man with a clinical suspicion of ankylosing spondylitis but with a persistence of increased inflammatory markers. In this case, (18)F-FDG-PET/CT revealed multiple hypermetabolic lesions in axial skeleton, lymph nodes, and the lung, suggestive of either disseminated tuberculo...

متن کامل

Ankylosing spondylitis and central core disease: case report.

Ankylosing spondylitis (AS) is an inflammatory disorder of unknown cause that primarily affects the axial skeleton. Neurological manifestations of AS are usually related to spinal deformities. Previous studies of the paraspinal muscles of AS patients showed muscle fiber atrophy, and core fibers. On the other hand, central core disease (CCD) is a genetic condition that primarily involves the ske...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:

دوره   شماره 

صفحات  -

تاریخ انتشار 2011